Continuous Column Chromatography Systems

4C Continuous Chromatography System is a brand-new type of chromatography system with design and features that offers superior separation performance compared to traditional batch techniques. MCPC chromatography system is a specialized chromatography system, used in gel filtration chromatography, when the packing height exceeds 50cm or more of the chromatography column

• The system is designed to provide robust process control during this critical downstream step.
• Continuous flow: Continuous flow of sample through the column. Ensures even distribution of sample and a higher utilization of the stationary phase.
• Higher throughput: A larger amount of sample can be processed per unit time, increasing the overall productivity.
• Smaller column size: 4C operate at higher flow rates, which leads to faster separations and smaller columns.
• Better efficiency: Due to the higher utilization of the stationary phase. as the sample flows through the entire length of the column.
• Use up to 4 Lab specification columns, control function through the system, each column can be switched in the steps of loading/elution/washing/regeneration at the same time.
• Superior automation and control features – provide robust process control during critical downstream step.
• Automated systems can precisely control critical parameters, leading to reproducible and optimized separations. Control in real-time allows for better control over the separation process and improved separation performance.
• Small system footprint: Switch functions are realized by a specially designed compact block valve containing 26 integrated valves.
• Custom-designed Process scale 4C Continuous Chromatography available on request.
• The system is designed to drastically reduce pre-elution and post-elution processing times for gel filtration chromatography media.
• The system uses two combinable systems to select different automatic programs for separate and combined operations during elution/sample loading/processing.
• It supports multiple chromatographic columns to load samples in series, which greatly increases the sample load of the chromatographic packing and improves the utilization efficiency of the packing.
• Human-machine interface (HMI) commands to record key process parameters.
• The program of the system software realizes the continuity of the sample loading step through the automatic program control, such as the UV value target.